About PSILORIS

Mission

PSILORIS exists to centralize careful, citation-backed education about psilocybin and mental health. The project tracks where evidence looks promising, where candidates still need rigorous trials, and where current science and safety standards argue against use.

It also maintains a curated world map of legalization and policy status so readers can separate scientific interest from local law.

Evidence methodology

• Promising — replicated or strong controlled clinical signals specific to the indication.
• Candidate — plausible biology or early signal without adequate modern controlled evidence.
• Mixed — conflicting findings or highly population-dependent results.
• Negative — risk/benefit currently argues against therapeutic use for that indication.

Peer-reviewed citations and anecdotal reports are visually and linguistically separated. Anecdotes never upgrade an evidence bucket on their own.

Limitations

This site is not a systematic review engine, a clinic directory, or a prescribing service. Content is curated and versioned in-repository. Legalization records cover a starter set of jurisdictions and will expand over time; unmarked countries mean “not yet curated,” not “known legal.”

Origin

PSILORIS is informed by lived experience with conventional psychiatric care and the wider clinical literature on psychedelic medicines. Personal stories may later appear only in carefully reviewed, consented forms — never as substitutes for evidence.

Read the safety and disclaimer page before exploring condition content.